Mitochondrial Medicine 2021 Virtual
Meet the Scientific Program Faculty
May 7 and May 21 - Noon to 2:00pm EDT
June 4 and June 18 - Noon to 2:00pm EDT
Bill Copeland, PhD
2021 Course Chair
National Institute of Environmental Health Sciences, Durham, DC
Friday, May 7, 2021 - 12:00 PM to 1:30 PM EDT
Mitochondria and Metabolism Platform
Dave Pagliarini, PhD
Washington University School of Medicine, St. Louis, MO
Mitochondrial Systems Biochemistry
Heather Christofk, PhD
University of California Los Angeles
Los Angeles, CA
Targeting Cancer Asparagine Dependence
Joshua Rabinowitz, MD, PhD
Princeton University
Princeton, NJ
TCA Cycle Fuels and Fluxes
Poster Abstract Presentations - May 7 - 1:30pm EDT
Abstract Presentations with Live Q&A
- Synthetic Messenger RNA Rescues Very Long-Chain Acyl-CoA Dehydrogenase Deficiency in Fibroblasts from Patients and a Murine Model, Xuejun Zhao
- Maladaptive Nutrient Signaling Sustains the m.3243A>G mtDNA Mutation, Chih-Yao Chung
- The gnomAD Database of Mitochondrial DNA Variation from 56,434 Individuals, Sarah Calvo
Friday, May 21, 2021 - 12:00 PM to 1:30 PM EDT
Mitochondria and Metabolism Platform
Eric Schon, PhD
Columbia University
New York, NY
Mitochondria in Alzheimer Disease: It's Not What You Think
Jared Rutter, PhD
University of Utah
Salt Lake City, UT
Mitochondria, Metabolism and Cellular Decisions
Anu Suomalainen, MD, PhD
University of Helsinki
Helsinki, Finland
Mitochondria and Metabolism - Topic TBD
Poster Abstract Presentations - May 21 - 1:30pm EDT
Abstract Presentations with Live Q&A
- A Cardiolipin-Binding Peptide Improves Cellular Bioenergetics in Mitochondrial Trifunctional Protein (TFP)-Deficient Mice and Patient Fibroblasts, Meicheng Wang
- Mitochondrial Protein Import Clogging as a Mechanism of Disease, Liam Coyne
- SLC25A46 Organizes a Platform for Mitochondrial Membrane Dynamics and Lipid Remodeling, Jana Schuettpelz
Friday, June 4, 2021 - 12:00 PM to 1:30 PM EDT
Gene Editing/Gene Therapy Platform
Carlos Moraes, PhD
University of Miami
Miami, FL
Progress on Gene Therapy for mtDNA Diseases
Steven Gray, PhD
University of Texas Southwestern Medical Center, Dallas, TX
Gene Therapy for SURF1-related Leigh Syndrome
Mickael Decressac, PhD
Grenoble Institute of Neuroscience (GIN), France
Towards Gene Therapy for Leigh Syndrome
Poster Abstract Presentations - June 4 - 1:30pm EDT
Abstract Presentations with Live Q&A
- Modulation of the Nuclear Epigenome as a New Strategy for Mitochondrial DNA Heteroplasmy Shift, Lia Mayorga
- Assessment of Lenadogene Nolparvovec (rAAV2/2-ND4) Gene Therapy Efficacy in Leber Hereditary Optic Neuropathy Using an External Control Group, Mark Moster
- Gene Replacement Therapy for SURF1-Related Leigh Syndrome Using AAV9, Qinglan Ling
Friday, June 18, 2021 - 12:00 PM to 1:30 PM EDT
Mitochondria in Stress Platform
Vamsi Mootha, MD
Harvard Medical School
Boston, MA
Hypoxia as a Therapy for Mitochondrial Disease
Phillip West, PhD
Texas A&M University College of Medicine, Bryan, TX
Mitochondrial Control of Innate Immunity and Inflammation
Poster Abstract Presentations - June 18 - 1:30pm
Abstract Presentations with Live Q&A
- Characterization of Two Variants in the Mitochondrial Topoisomerase Gene TOP1MT Reveal a Potential Involvement in Human Pathology, Iman Al Khatib
- Identification of Novel Compounds to Treat Rare Mitochondrial Diseases, Arwen Gao
- COVID-19 Topic - TBD