Mitochondrial Medical and Scientific Meetings

Upcoming UMDF Bench-to-Bedside Seminars:

The UMDF Bench-to-Bedside Seminar Series follows in the footsteps of the highly successful Mito Friday Seminar Series launched earlier this year. This program addresses a need for increased scientific discussion of important mitochondrial research being conducted around the world. The Bench-to-Bedside (BtB) seminars will take place monthly and typically last one hour.

Recordings from UMDF Bench-to-Bedside webcasts will be made available for a limited time as on-demand or through this web page. Availability of recordings is at the discretion of our presenters.

Researchers and clinicians that would like to suggest a topic or theme are encouraged to contact UMDF at [email protected].

If you are interested in submitting an abstract for consideration as a future presenter, please utilize our online portal by clicking here.

Bench-to-Bedside programming will resume in September of 2021.

Previous UMDF Bench-to-Bedside Seminars:

Friday, April 16, 2021

Advancements in Mitochondrial DNA Transfer

Moderator: Brett Kaufman, PhD

Topics & Presenters

New Developments in Mitochondrial DNA Transfer

Michael Teitell, MD, PhD, UCLA

Mitochondrial DNA Intercellular Traveling

Jose Antonio Enriquez, PhD, Spanish National Center for Cardiovascular Research

Thursday, March 18, 2021

Fluid Genomes: mtDNA Dynamics and Respiratory Chain Activity in Blood Leukocytes

Moderator: Peter McGuire, MD

Topics & Presenters:

Cell-type Specific Mitochondrial Phenotypes in Circulating Human Leukocytes

Martin Picard, PhD, Columbia University, New York, NY

Dual Genome 'Omics: the Heteroplasmy Problem

Melissa Walker, MD, PhD, Harvard Medical School, Boston, MA

Thursday, February 18, 2021

Topic: Novel Insights from the Mitochondrial Interactome 

Moderator: Brett Kaufman, PhD

Presenters & Topics:

Martin Ott, PhD, Stockholm University, Stockholm, Sweden

Molecular Connectivity of Mitochondrial Gene Expression and OXPHOS Biogenesis

Hana Antonicka, MSc, PhD, The Neuro & McGill University, Montreal, Quebec, Canada

A High-Density Human Mitochondrial Proximity Interaction Network

Friday, January 15, 2021

Topic: Novel aspects of mitochondrial NAD+ Biology

Moderator: Brett Kaufman, PhD


Joseph A. Baur, PhD, University of Pennsylvania, Philadelphia, PA

Anu Suomalainen-Wartiovaara, MD, PhD, University of Helsinki, Helsinki, Finland

Friday, December 11, 2020

Topic: Nuclear Genome-wide Associations with Mitochondrial Heteroplasmy 

Moderator: Brett Kaufman, PhD


Priyanka Nandakumar, PhD, 23andMe, California 

Neal Sondheimer, MD, PhD, The Hospital for Sick Children, Toronto, ON, Canada

Friday, November 20, 2020

Topic: Clinical and Cellular Phenotypes of m.3243A>G

Moderator: Brett Kaufman, PhD

Presenters and Topics:

Michio Hirano, MD, Columbia University, New York, NY

Clinical Manifestations and Natural History of m.3243A>G

Tamas Kozicz, MD, PhD, Mayo Clinic, Rochester, MN

m.3243A>G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity

Friday, October 9, 2020

Topic: Mitochondrial Targets and Defenses in the Time of COVID

  • Moderator: Bruce H. Cohen, MD, Akron Children's Hospital, Akron, OH


  • Robert K. Naviaux, PhD, University of California San Diego, San Diego, CA
  • Keshav Singh, PhD, University of Birmingham, Birmingham, AL

Monday, September 21, 2020

  • Topic: Discovery and Implications of Interbacterial Deaminase Toxins

Presenter: Joseph Mougous, PhD, University of Washington, Seattle, WA

  • Topic: A Bacterial Cytidine Deaminase Toxin Enables CRISPR-Free Mitochondrial Base Editing

Presenter: David R. Liu, PhD, Harvard University, Cambridge, MA

Friday, August 28, 2020 

UMDF Funded Projects:

  • Investigating intrinsic and extrinsic factors influencing mitochondrial heteroplasmy in mt-tRNA mutation-linked disease - Dr. Kinsley Belle, Postdoctoral Fellow, Stanford University
  • Mechanisms of protein assembly underlying mitochondrial DNA maintenance but altered in early-onset neurodegenerative disorders - Dr. Breann Brown, Assistant Professor, Vanderbilt University
  • Implementation of the CRISPR gene editing technology – Edit Plasmids - toward the curing of mitochondrial diseases caused by mutations in mitochondrial DNA - Dr. Hajime Sakai, CEO, NAPIGEN

Friday, June 19, 2020

  • Topic: Mitochondrial Control of Innate Immune Responses in Disease and Aging

Presenter: A. Phillip West, PhD, Assistant Professor, Department of Microbial Pathogenesis & Immunology, Texas A&M University

  • Topic: A Quantitative Tissue-Specific Landscape of Protein Redox Regulation During Aging

Presenter: Ed Chouchani, PhD, Assistant Professor of Cancer Biology and Cell Biology, Dana Farber Cancer Institute and Harvard University

Friday, June 5, 2020

  • Topic: Mouse Models of Mitochondrial DNA Disease

Presenter: James Stewart, PhD, Research Group Leader, Max Planck Institute for Biology of Ageing

  • Topic: Mitochondrial DNA Heteroplasmy in Disease and Targeted Nuclease-Based Therapeutic Approaches

Presenter: Carlos Moraes, PhD, Lichtenstein Professor of Neurology, Department of Neurology, University of Miami Miller School of Medicine

Friday, May 22, 2020

  • Topic: Translational and Clinical Perspectives on Mitochondrial DNA Deletions During Normal Aging and POLG Disease
  • Presenters: Bruce H. Cohen, MD, Akron Children's Hospital and William Copeland, PhD, NIEHS